[Mnemonic] Types of porphyria and Heme synthesis pathway

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Types of porphyria


All---------------Acute Intermittent Porphyria

Congenital------Congenital erythropoetic Porphyria

Porphyrias------Porphyria Cutanea Tarda

Have------------Hereditary Coprophyria

Variable---------Variegate Porphyria

Presentation----Protoporhyria

Uroprophyrinogen I synthase..............Acute I.Porphyra
Uroporphyrinogen III co-synthase.......Congenital erythropoetic Porphyria
Uroporphyrinogen III decarboxylase....Porphyria Cutanea Tarda
Coprophyrinogen III oxidase...............Hereditary Coprophyria
Protoporhyrinogen oxidase.................Variegate Porphyria
Ferrochelatase....................................Protoporhyria

Porphyrias: acute intermittent porphyria symptoms 5 P's:

Pain in abdomen

Polyneuropathy

Psychologial abnormalities

Pink urine

Precipitated by drugs (eg barbiturates, oral contraceptives, sulpha drugs)


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